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Tri-Heart Plus
(1415)
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What is Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets?
Tri-Heart Plus® (ivermectin/pyrantel) chewable tablets are indicated for use in prevention of canine heartworm caused by Dirofilaria immitis and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense) in dogs and in puppies six weeks of age.
Suitable for:
Dogs and Puppies (6+ weeks of age)
Benefits:
- Contains the same active ingredients, ivermectin/pyrantel, as the leading competitor, but at a lower price.
- Prevents heartworm disease, treats, and controls roundworms and hookworms.
- Kills heartworm larvae before they reach your dog’s heart.
- Enjoy year-round protection for your dog, with monthly treatments.
- Easy-to-give, beef-flavored, chewable tablet that your dog will enjoy.
- 94% of dogs love the chewable tablets. In a taste test, dogs proved to have no preference for Tri-Heart Plus®; & HEARTGARD®.
- Safe for dogs with beef allergies.
- Available in three dosage strengths for dogs of different weights.
How do Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets work?
Tri-Heart Plus® is a proven, cost-effective and easy-to-administer chewable tablet that helps keep your dog free of heartworm and other dangerous parasites. Tri-Heart Plus® chewable tablets contain a proven combination of ingredients to protect your dog and ensure your complete peace of mind. Ask your veterinarian about Tri-Heart Plus® today.
Cautions:
The following adverse reactions have been reported following the use of ivermectin at the recommended dose: depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions and hypersalivation. All dogs should be tested for heartworm infection before starting a preventive program. In a small percentage of ivermectin/pyrantel treated dogs, digestive and neurological side effects may occur.
Brand Name:
Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets
Generic Name:
Ivermectin, Pyrantel
What is the most important thing I should know about Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets?
The most important thing to know about Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets is that it is a combination medication used to prevent heartworm disease and treat and control roundworm and hookworm infections in dogs. The active ingredients, ivermectin and pyrantel, work together to kill heartworm larvae before they mature and to treat intestinal worms. It's crucial to administer this medication according to the prescribed schedule (usually once a month) to maintain its effectiveness. Additionally, a dog should be tested for existing heartworm infection before starting the medication, as severe adverse reactions can occur if administered to a heartworm-positive dog. Always consult with a veterinarian before starting or changing any medication regimen for your pet.
What should I discuss with my veterinarian before giving Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets to my pet?
Always consult with a veterinarian before starting or changing any medication regimen for your pet.
- Heartworm Testing: Ensure your dog has been tested for heartworms. Administering Tri-Heart Plus® to a dog that is already infected with heartworms can lead to severe adverse reactions.
- Breed Sensitivities: Some dog breeds, particularly Collies and related breeds, may have a genetic sensitivity to ivermectin. Discuss your dog's breed and any potential risks associated with ivermectin sensitivity.
- Current Medications: Inform your veterinarian about any other medications or supplements your dog is currently taking, as there could be interactions or contraindications.
- Health History: Discuss your dog's overall health, including any history of illnesses or allergies, as this can
How should Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets be given?
Tri-Heart Plus®; Plus should be administered orally at monthly intervals during the period of the year when mosquitoes
(vectors), potentially carrying infective heartworm larvae, are active at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The initial dose must be given within a month (30 days) after the dog’s first exposure to mosquitoes. The final dose must be given
within a month (30 days) after the dog’s last exposure to mosquitoes.
What are the potential side effects of Tri-Heart Plus® (ivermectin/pyrantel)Chewable Tablets?
Side effects of Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets are rare at the recommended heartworm prevention dose, but may include lethargy, limpness, salivation, shaking, diarrhea, decreased appetite, licking lips, and belching. Higher doses in dogs may cause tremors, dilated pupils, loss of body weight, or death.
What happens if I miss giving a dose of Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets?
If the interval between doses exceeds 30 days, the efficacy of ivermectin can be reduced. Therefore, for optimal performance, the chewable tablet must be given once a month, on or about the same day of the month. If treatment is delayed, whether by a few days or many, please contact your veterinarian, as immediate treatment with Tri-Heart Plus® chewable tablets and resumption of the recommended dosing regimen minimizes the opportunity for the development of adult heartworms.
What happens if I overdose my pet on Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets?
Contact your veterinarian immediately if accidental overdose occurs. To reduce the risk of accidental overdose in situations where more than one person may administer Tri-Heart Plus®, we suggest ticking off the date on a specially marked calendar or making some other note to indicate that the dose has been given. Make a habit of checking with the other pet caregivers in your household before giving any medications to your pet.
What should I avoid while giving Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets to my pet?
Do not administer Tri-Heart Plus® if your dog has not been tested for heartworms or if the test results are positive. This can cause severe reactions due to the presence of mature heartworms. Do not use Tri-Heart Plus® past its expiration date. The effectiveness of the medication may decrease, and it could be harmful to your dog. Some breeds, like Collies and other herding breeds, may have a genetic sensitivity to ivermectin. Avoid giving the medication to these breeds without consulting your veterinarian.
What other drugs will affect Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets?
Avoid giving your dog any other medications, especially those containing ivermectin or similar compounds, without consulting your veterinarian to prevent potential drug interactions.
Storage
Store at controlled room temperatures of 59° - 86°F. Protect product from light.
Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets Directions:
- Give your dog one beef-flavored chewable Tri-Heart Plus® tablet on the same day each month during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active, at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight.
- Remove only one chewable tablet at a time from the blister card. Because most dogs find Tri-Heart Plus® palatable, the product can be offered to the dog by hand. Alternatively, it may be added intact to a small amount of dry food or placed in the back of the dog’s mouth for forced swallowing.
- Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
- The initial dose must be given within a month (30 days) after the dog’s first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog’s last exposure to mosquitoes.
- The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms can be found in the table below.
Tip:
Incorporate the administration of Tri-Heart Plus® into a positive, routine activity that your dog enjoys, such as a monthly "spa day" or special treat time. For example, you can pair giving the tablet with a favorite treat, a fun grooming session, or a playtime ritual. This creates a positive association with taking the medication, making it easier for your dog to accept the tablet willingly each month. Additionally, by integrating the medication into a routine event, you're less likely to forget a dose, ensuring consistent heartworm and parasite prevention.
TRI-HEARTTri-Heart Plus® PLUS (ivermectin/pyrantel) Chewable Tablets Dosage
| Weight | Dosage | Ivermectin Content | Pyrantel Content | Color Coding on Box |
|---|---|---|---|---|
| Up to 25 lbs | Give 1 chewable every month | 68 mcg | 57 mg | Blue Box |
| 26-50 lbs | Give 1 chewable every month | 136 mcg | 114 mg | Green Box |
| 51-100 lbs | Give 1 chewable every month | 272 mcg | 227 mg | Brown Box |
| Over 100 lbs | Give combination of chewables based on weight | See packaging | See packaging | See packaging |
| Cats |
|---|
| Do not use! |
| Horses |
|---|
| Do not use! |
Tri-Heart Plus® (ivermectin/pyrantel) Chewable Tablets Ingredients:
| Active Ingredients (per chewable tablet) | Amount |
|---|---|
| Ivermectin | 68 mcg |
| Pyrantel | 57 mg |
| Active Ingredients (per chewable tablet) | Amount |
|---|---|
| Ivermectin | 136 mcg |
| Pyrantel | 114 mg |
| Active Ingredients (per chewable tablet) | Amount |
|---|---|
| Ivermectin | 272 mcg |
| Pyrantel | 227 mg |
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